Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate carboxypeptidase 2' and Ligand = 'BDBM479456'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM479456 (US10894807, ID P276) Show SMILES OC(=O)CCC(NC(=O)NC(CCCCNC(=O)CC(CC(=O)NCCCC[C@@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)NC(=O)Cn1cc(CCCF)nn1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C36H55FN10O17/c37-13-5-6-20-18-47(46-45-20)19-28(50)40-21(16-26(48)38-14-3-1-7-22(31(55)56)41-35(63)43-24(33(59)60)9-11-29(51)52)17-27(49)39-15-4-2-8-23(32(57)58)42-36(64)44-25(34(61)62)10-12-30(53)54/h18,21-25H,1-17,19H2,(H,38,48)(H,39,49)(H,40,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60)(H,61,62)(H2,41,43,63)(H2,42,44,64)/t21?,22-,23?,24+,25?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Siemens Medical Solutions USA, Inc. US Patent					Assay Description The inhibitory activity of all compounds was determined using a fluorescent assay of human PSMA activity. The enzyme used in the assay was purchased ...				US Patent US10894807 (2021) BindingDB Entry DOI: 10.7270/Q2SN0D25
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