Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate carboxypeptidase 2 (Homo sapiens (Human)) | BDBM50106556 (2-Phosphonomethyl-hexanedioic acid | CHEMBL334737) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Curated by ChEMBL | Assay Description Binding affinity to NAALADase | J Med Chem 55: 9510-20 (2012) Article DOI: 10.1021/jm300710j BindingDB Entry DOI: 10.7270/Q28053R3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Glutamate carboxypeptidase 2 (Rattus norvegicus) | BDBM50106556 (2-Phosphonomethyl-hexanedioic acid | CHEMBL334737) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against rat brain NAALADase (Folate hydrolase) | J Med Chem 44: 4170-5 (2001) BindingDB Entry DOI: 10.7270/Q2D21WX8 | |||||||||||
More data for this Ligand-Target Pair |