Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate dehydrogenase 2, mitochondrial' and Ligand = 'BDBM383202'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate dehydrogenase 2, mitochondrial (Human)	BDBM383202 (US10278968, Compound 730 | US10793535, Cmpd ID 730) Show SMILES Oc1cc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccn4)s3)nn2)cc(OC(F)(F)F)c1 Show InChI InChI=1S/C26H24F3N7O4S/c27-26(28,29)40-20-12-16(11-19(37)15-20)13-22(38)31-21-9-8-17(33-34-21)5-1-2-7-24-35-36-25(41-24)32-23(39)14-18-6-3-4-10-30-18/h3-4,6,8-12,15,37H,1-2,5,7,13-14H2,(H,31,34,38)(H,32,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences, Inc. US Patent					Assay Description Glutaminase reaction buffer was prepared [50 mM Tris-HCl pH 8.8, 150 mM K2HPO4, 0.25 mM EDTA, 0.1 mg/ml BSA (Calbiochem no. 2960), 1 mM DTT, 2 mM NAD...				US Patent US10793535 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2KV5
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