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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit' and Ligand = 'BDBM50459031'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit


(Homo sapiens (Human))		BDBM50459031
PNG
(CHEMBL4216837)
Show SMILES Fc1cc(cc2CC(=O)Nc12)-c1c(Cl)cccc1OC(F)(F)F
Show InChI InChI=1S/C15H8ClF4NO2/c16-9-2-1-3-11(23-15(18,19)20)13(9)7-4-8-6-12(22)21-14(8)10(17)5-7/h1-5H,6H2,(H,21,22)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a



Janssen Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Modulation of recombinant human GluA1 flop isoform/TARPgamma8 expressed in HEK293F cells assessed as blockade of glutamate-induced calcium flux by ca...

ACS Med Chem Lett 9: 821-826 (2018)


Article DOI: 10.1021/acsmedchemlett.8b00215
BindingDB Entry DOI: 10.7270/Q2ZW1PJ3
More data for this
Ligand-Target Pair