Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor 1' and Ligand = 'BDBM426272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 1 (Homo sapiens (Human))	BDBM426272 (4-[3-(1H-Indazol-5-yl)-4-methyl-2-phenyl-pyrazolo[...) Show SMILES Cc1cnc(N2CCOCC2)n2nc(c(-c3ccc4[nH]ncc4c3)c12)-c1ccccc1 Show InChI InChI=1S/C24H22N6O/c1-16-14-25-24(29-9-11-31-12-10-29)30-23(16)21(22(28-30)17-5-3-2-4-6-17)18-7-8-20-19(13-18)15-26-27-20/h2-8,13-15H,9-12H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...				US Patent US10513523 (2019) BindingDB Entry DOI: 10.7270/Q2KW5JDR
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