Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells | J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2 | J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx ... | J Med Chem 50: 1558-70 (2007) Article DOI: 10.1021/jm061041u BindingDB Entry DOI: 10.7270/Q2X34Z8Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2 | J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |