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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor 2' and Ligand = 'BDBM50318266'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor 2


(Rattus norvegicus)
BDBM50318266
PNG
((+)-2-Amino-5-(4-hydroxy-1,2,5-oxadiazol-3-yl)pent...)
Show SMILES NC(CCCc1no[nH]c1=O)C(O)=O
Show InChI InChI=1S/C7H11N3O4/c8-4(7(12)13)2-1-3-5-6(11)10-14-9-5/h4H,1-3,8H2,(H,10,11)(H,12,13)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Torino

Curated by ChEMBL


Assay Description
Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting


J Med Chem 53: 4110-8 (2010)


Article DOI: 10.1021/jm1001452
BindingDB Entry DOI: 10.7270/Q2RR206G
More data for this
Ligand-Target Pair
Glutamate receptor 2


(Homo sapiens (Human))
BDBM50318266
PNG
((+)-2-Amino-5-(4-hydroxy-1,2,5-oxadiazol-3-yl)pent...)
Show SMILES NC(CCCc1no[nH]c1=O)C(O)=O
Show InChI InChI=1S/C7H11N3O4/c8-4(7(12)13)2-1-3-5-6(11)10-14-9-5/h4H,1-3,8H2,(H,10,11)(H,12,13)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4.91E+5n/an/an/an/a



Universit£ degli Studi di Torino

Curated by ChEMBL


Assay Description
Activity at recombinant iGluR2 receptor expressed in Xenopus laevis oocytes using holding potential of -15 to -20 mV by TEVC electrophysiology


J Med Chem 53: 4110-8 (2010)


Article DOI: 10.1021/jm1001452
BindingDB Entry DOI: 10.7270/Q2RR206G
More data for this
Ligand-Target Pair