Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor 3' and Ligand = 'BDBM50512940'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor 3 (RAT)	BDBM50512940 (CHEMBL3742450) Show SMILES Cn1nc(O)c(CC(N)C(O)=O)n1 Show InChI InChI=1S/C6H10N4O3/c1-10-8-4(5(11)9-10)2-3(7)6(12)13/h3H,2,7H2,1H3,(H,9,11)(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 3 (Homo sapiens (Human))	BDBM50512940 (CHEMBL3742450) Show SMILES Cn1nc(O)c(CC(N)C(O)=O)n1 Show InChI InChI=1S/C6H10N4O3/c1-10-8-4(5(11)9-10)2-3(7)6(12)13/h3H,2,7H2,1H3,(H,9,11)(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
University of Turin Curated by ChEMBL					Assay Description Agonist activity at GluA3 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...				J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06
					More data for this Ligand-Target Pair				3D Structure (crystal)