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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor 4' and Ligand = 'BDBM50158554'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor 4


(Rattus norvegicus)
BDBM50158554
PNG
(CHEMBL224688 | {2-[3-(3-bromophenyl)ureido]-4-chlo...)
Show SMILES OC(=O)Cc1ccc(Cl)cc1NC(=O)Nc1cccc(Br)c1
Show InChI InChI=1S/C15H12BrClN2O3/c16-10-2-1-3-12(7-10)18-15(22)19-13-8-11(17)5-4-9(13)6-14(20)21/h1-5,7-8H,6H2,(H,20,21)(H2,18,19,22)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



The Danish University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...


J Med Chem 47: 6948-57 (2004)


Article DOI: 10.1021/jm030638w
BindingDB Entry DOI: 10.7270/Q2SQ8ZVT
More data for this
Ligand-Target Pair