BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50149689'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50149689 (2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dih...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Ltd Curated by ChEMBL					Assay Description Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptor				Bioorg Med Chem Lett 14: 3953-6 (2004) Article DOI: 10.1016/j.bmcl.2004.05.053 BindingDB Entry DOI: 10.7270/Q2FT8KG8
Gedeon Richter Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50149689 (2-(4-Benzyl-piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dih...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
I2BM Curated by ChEMBL					Assay Description Displacement of [3H]-Ro-256981 from recombinant NR1/NR2B receptor				Eur J Med Chem 46: 2295-309 (2011) Article DOI: 10.1016/j.ejmech.2011.03.013 BindingDB Entry DOI: 10.7270/Q2M32ZMN
I2BM Curated by ChEMBL					More data for this Ligand-Target Pair