Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50180882'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50180882 (CHEMBL3818816) Show SMILES c1ccncc1.[H][C@]12CC[C@@]3([H])[C@H](C)[C@](C)(CC[C@]3([H])[C@@]1(C)CC[C@H](C2)OS(O)(=O)=O)C(=O)OC |r| Show InChI InChI=1S/C19H32O6S.C5H5N/c1-12-15-6-5-13-11-14(25-26(21,22)23)7-9-19(13,3)16(15)8-10-18(12,2)17(20)24-4;1-2-4-6-5-3-1/h12-16H,5-11H2,1-4H3,(H,21,22,23);1-5H/t12-,13+,14+,15-,16-,18-,19-;/m0./s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of recombinant rat GluN1a/GluN2B co-expressed in HEK293 cells assessed as suppression of glutamate-induced current by patch-clamp method				J Med Chem 59: 4724-39 (2016) Article DOI: 10.1021/acs.jmedchem.6b00079 BindingDB Entry DOI: 10.7270/Q28K7C05
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