Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50180889'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50180889 (CHEMBL3818191) Show SMILES [H][C@@]12CC[C@]3([H])C[C@@H](CC[C@]3(C)[C@@]1([H])CC[C@](C)(COC)C2)OC(=O)CCC(O)=O |r| Show InChI InChI=1S/C22H36O5/c1-21(14-26-3)10-9-18-15(13-21)4-5-16-12-17(8-11-22(16,18)2)27-20(25)7-6-19(23)24/h15-18H,4-14H2,1-3H3,(H,23,24)/t15-,16+,17+,18-,21-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of recombinant rat GluN1a/GluN2B co-expressed in HEK293 cells assessed as suppression of glutamate-induced current by patch-clamp method				J Med Chem 59: 4724-39 (2016) Article DOI: 10.1021/acs.jmedchem.6b00079 BindingDB Entry DOI: 10.7270/Q28K7C05
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