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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50461812'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50461812
PNG
(CHEMBL4225526)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCCCCCC(O)=O |r,t:19|
Show InChI InChI=1S/C29H44O5/c1-19(30)23-12-13-24-22-11-10-20-18-21(34-27(33)9-7-5-4-6-8-26(31)32)14-16-28(20,2)25(22)15-17-29(23,24)3/h10,21-25H,4-9,11-18H2,1-3H3,(H,31,32)/t21-,22-,23+,24-,25-,28-,29+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.93E+4n/an/an/an/a



Institute of Physiology of the Czech Academy of Sciences

Curated by ChEMBL


Assay Description
Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...

J Med Chem 61: 4505-4516 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00255
BindingDB Entry DOI: 10.7270/Q2Z03BTB
More data for this
Ligand-Target Pair