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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50461815'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)		BDBM50461815
PNG
(CHEMBL4227806)
Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCCCCC(O)=O |r,t:19|
Show InChI InChI=1S/C28H42O5/c1-18(29)22-11-12-23-21-10-9-19-17-20(33-26(32)8-6-4-5-7-25(30)31)13-15-27(19,2)24(21)14-16-28(22,23)3/h9,20-24H,4-8,10-17H2,1-3H3,(H,30,31)/t20-,21-,22+,23-,24-,27-,28+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.80E+4n/an/an/an/a



Institute of Physiology of the Czech Academy of Sciences

Curated by ChEMBL


Assay Description
Positive allosteric modulation of recombinant rat GluN1alpha/GluN2B receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced ...

J Med Chem 61: 4505-4516 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00255
BindingDB Entry DOI: 10.7270/Q2Z03BTB
More data for this
Ligand-Target Pair