Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2B' and Ligand = 'BDBM50498433'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498433 (CHEMBL3593892) Show SMILES c1ccncc1.[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OS(O)(=O)=O)[C@H](C)CC |r| Show InChI InChI=1S/C23H40O4S.C5H5N/c1-5-15(2)19-8-9-20-18-7-6-16-14-17(27-28(24,25)26)10-12-22(16,3)21(18)11-13-23(19,20)4;1-2-4-6-5-3-1/h15-21H,5-14H2,1-4H3,(H,24,25,26);1-5H/t15-,16-,17-,18+,19-,20+,21+,22+,23-;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
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