BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1/2D' and Ligand = 'BDBM50238363'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))		BDBM50238363
PNG
(CHEMBL4099510)
Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1
Show InChI InChI=1S/C29H30F3NO3S/c1-4-34-23-8-10-24(11-9-23)35-18-27-26-13-12-25(36-19(2)3)17-20(26)14-15-33(27)28(37)21-6-5-7-22(16-21)29(30,31)32/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 450n/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...

J Med Chem 60: 5556-5585 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00239
BindingDB Entry DOI: 10.7270/Q298898H
More data for this
Ligand-Target Pair