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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50005047'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50005047
PNG
(7-Chloro-5-iodo-4-phenylacetylamino-1,2,3,4-tetrah...)
Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)Cc2ccccc2)c2c(I)cc(Cl)cc2N1
Show InChI InChI=1S/C18H16ClIN2O3/c19-11-7-12(20)17-13(8-11)21-15(18(24)25)9-14(17)22-16(23)6-10-4-2-1-3-5-10/h1-5,7-8,14-15,21H,6,9H2,(H,22,23)(H,24,25)/t14-,15+/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 10n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.

J Med Chem 35: 1954-68 (1992)


BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair