Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50005081'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005081 (5,7-Dichloro-4-(3-naphthalen-1-yl-ureido)-1,2,3,4-...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)Nc2cccc3ccccc23)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C21H17Cl2N3O3/c22-12-8-14(23)19-16(9-12)24-18(20(27)28)10-17(19)26-21(29)25-15-7-3-5-11-4-1-2-6-13(11)15/h1-9,17-18,24H,10H2,(H,27,28)(H2,25,26,29)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to N-methyl-D-aspartate glutamate receptor from rat cortical membranes				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair