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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50042328'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50042328
PNG
(2-(7-Chloro-3-nitro-2-oxo-1,2,3,4-tetrahydro-quino...)
Show SMILES CN(C(=O)CC1C(C(=O)Nc2cc(Cl)ccc12)[N+]([O-])=O)c1ccccc1
Show InChI InChI=1S/C18H16ClN3O4/c1-21(12-5-3-2-4-6-12)16(23)10-14-13-8-7-11(19)9-15(13)20-18(24)17(14)22(25)26/h2-9,14,17H,10H2,1H3,(H,20,24)
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PubMed
n/an/a 1.84E+3n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards NMDA receptor to displace [3H]-L-689,560 from rat cortical membranes

J Med Chem 36: 3397-408 (1993)


BindingDB Entry DOI: 10.7270/Q2Z89BFF
More data for this
Ligand-Target Pair