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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50056664'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50056664
PNG
(7-Chloro-2-oxo-3-phenyl-1,2-dihydro-quinoline-4-ca...)
Show SMILES Clc1ccc2c(C(=O)NCc3ccccc3)c(-c3ccccc3)c(=O)[nH]c2c1
Show InChI InChI=1S/C23H17ClN2O2/c24-17-11-12-18-19(13-17)26-23(28)20(16-9-5-2-6-10-16)21(18)22(27)25-14-15-7-3-1-4-8-15/h1-13H,14H2,(H,25,27)(H,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...

J Med Chem 40: 754-65 (1997)


Article DOI: 10.1021/jm9605492
BindingDB Entry DOI: 10.7270/Q2J67G1J
More data for this
Ligand-Target Pair