Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50505140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Mus musculus)	BDBM50505140 (CHEMBL4526884) Show SMILES Fc1cc(ccc1Cl)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C19H16ClFN4O4/c20-13-3-2-12(10-14(13)21)24-5-7-25(8-6-24)18(27)17(26)22-11-1-4-15-16(9-11)29-19(28)23-15/h1-4,9-10H,5-8H2,(H,22,26)(H,23,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced...				Bioorg Med Chem Lett 29: 1143-1147 (2019) Article DOI: 10.1016/j.bmcl.2019.02.017 BindingDB Entry DOI: 10.7270/Q2P55RSV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50505140 (CHEMBL4526884) Show SMILES Fc1cc(ccc1Cl)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1 Show InChI InChI=1S/C19H16ClFN4O4/c20-13-3-2-12(10-14(13)21)24-5-7-25(8-6-24)18(27)17(26)22-11-1-4-15-16(9-11)29-19(28)23-15/h1-4,9-10H,5-8H2,(H,22,26)(H,23,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting met...				Bioorg Med Chem Lett 29: 1143-1147 (2019) Article DOI: 10.1016/j.bmcl.2019.02.017 BindingDB Entry DOI: 10.7270/Q2P55RSV
					More data for this Ligand-Target Pair