Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM521609'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM521609 (US11149054, Compound 4657) Show SMILES COC[C@H]1CC[C@](O)(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC[C@H]5C[C@@](O)(CC[C@]5(C)[C@H]4CC[C@]23C)C(F)(F)F)CC1 |r,wU:19.19,27.29,15.14,21.21,25.26,12.11,6.7,30.34,wD:16.16,21.35,10.10,6.6,3.2,(10.02,-1.37,;8.93,-.28,;7.44,-.68,;6.35,.41,;6.75,1.9,;5.66,2.99,;4.17,2.59,;4.17,4.13,;2.67,2.27,;1.64,3.41,;.13,3.09,;-.9,4.24,;-.34,1.63,;.56,.38,;-.34,-.86,;-1.81,-.39,;-3.14,-1.16,;-3.14,-2.7,;-4.48,-3.47,;-5.81,-2.7,;-7.14,-3.47,;-8.48,-2.7,;-9.57,-3.79,;-8.48,-1.16,;-7.14,-.39,;-5.81,-1.16,;-5.81,.38,;-4.48,-.39,;-4.48,1.15,;-3.14,1.92,;-1.81,1.15,;-1.65,2.68,;-10.02,-2.7,;-10.79,-1.36,;-10.79,-4.03,;-11.56,-2.7,;3.78,1.1,;4.86,.01,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA					Assay Description The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...				Citation and Details BindingDB Entry DOI: 10.7270/Q24X5BZR
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