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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM521617'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM521617
PNG
(US11149054, Compound 3886)
Show SMILES C[C@H](CC[C@@]1(O)CC[C@H](C)CC1)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C(F)(F)F |r,wU:19.20,27.30,15.15,21.22,25.27,12.12,4.3,30.35,wD:16.17,21.36,1.0,4.4,8.8,(.39,4.24,;1.42,3.09,;2.93,3.41,;3.96,2.27,;5.46,2.59,;5.46,4.13,;6.95,2.99,;8.04,1.9,;7.64,.41,;8.73,-.68,;6.15,.01,;5.06,1.1,;.94,1.63,;1.85,.38,;.94,-.86,;-.52,-.39,;-1.85,-1.16,;-1.85,-2.7,;-3.19,-3.47,;-4.52,-2.7,;-5.86,-3.47,;-7.19,-2.7,;-8.28,-3.79,;-7.19,-1.16,;-5.86,-.39,;-4.52,-1.16,;-4.52,.38,;-3.19,-.39,;-3.19,1.15,;-1.85,1.92,;-.52,1.15,;-.36,2.68,;-8.73,-2.7,;-9.5,-1.36,;-9.5,-4.03,;-10.27,-2.7,)|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 50.1n/an/an/an/a


TBA

Assay Description
The whole-cell patch-clamp technique was used to investigate the effects of positive allosteric modulating activity of test compounds on GlunN1/GluN2...

Citation and Details

BindingDB Entry DOI: 10.7270/Q24X5BZR
More data for this
Ligand-Target Pair