Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM383194'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM383194 (US10278968, Compound 722 | US10793535, Cmpd ID 722) Show SMILES COc1ccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccn4)s3)nn2)cc1OC(F)(F)F Show InChI InChI=1S/C27H26F3N7O4S/c1-40-20-11-9-17(14-21(20)41-27(28,29)30)15-23(38)32-22-12-10-18(34-35-22)6-2-3-8-25-36-37-26(42-25)33-24(39)16-19-7-4-5-13-31-19/h4-5,7,9-14H,2-3,6,8,15-16H2,1H3,(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 5594-607 (2008) BindingDB Entry DOI: 10.7270/Q27P91QX
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