Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM50150703'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50150703 (CHEMBL3770921) Show SMILES O=C(Cc1ccccc1)Nc1ccc(OC2CCN(CC2)c2ccc(NC(=O)Cc3ccccc3)nc2)cn1 Show InChI InChI=1S/C31H31N5O3/c37-30(19-23-7-3-1-4-8-23)34-28-13-11-25(21-32-28)36-17-15-26(16-18-36)39-27-12-14-29(33-22-27)35-31(38)20-24-9-5-2-6-10-24/h1-14,21-22,26H,15-20H2,(H,32,34,37)(H,33,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant HIs-tagged human GAC (residue 72-603 aa) expressed in Escherichia coli after 10 mins using glutamine as substrate				Bioorg Med Chem 24: 1819-39 (2016) Article DOI: 10.1016/j.bmc.2016.03.009 BindingDB Entry DOI: 10.7270/Q2DZ0B5C
					More data for this Ligand-Target Pair