Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase' and Ligand = 'BDBM50237482'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50237482 (CHEMBL4093854) Show SMILES COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cc(N)nc(N)c1 Show InChI InChI=1S/C24H33N7O2S/c1-17-15-27-16-31(17)10-5-9-28-24(34)29-19-7-8-20(21(14-19)32-2)33-11-4-3-6-18-12-22(25)30-23(26)13-18/h7-8,12-16H,3-6,9-11H2,1-2H3,(H4,25,26,30)(H2,28,29,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...				J Med Chem 60: 2573-2590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00098 BindingDB Entry DOI: 10.7270/Q23X88X9
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