Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase' and Ligand = 'BDBM50237486'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl-peptide cyclotransferase (Homo sapiens (Human))	BDBM50237486 (CHEMBL4077433) Show SMILES COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCNCC1 Show InChI InChI=1S/C21H32N6O2S/c1-17-15-23-16-27(17)9-3-6-24-21(30)25-18-4-5-19(20(14-18)28-2)29-13-12-26-10-7-22-8-11-26/h4-5,14-16,22H,3,6-13H2,1-2H3,(H2,24,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...				J Med Chem 60: 2573-2590 (2017) Article DOI: 10.1021/acs.jmedchem.7b00098 BindingDB Entry DOI: 10.7270/Q23X88X9
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