Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutathione S-transferase A1/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D]' and Ligand = 'BDBM214645'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione S-transferase A1/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] (Homo sapiens (Human))	BDBM214645 (US9284319, R2 | US9730929, Example R3 | US9783543,...) Show SMILES C1CCC(CC1)Nc1ccc2ncc(-c3ccncc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-2-4-14(5-3-1)20-16-6-7-17-19-12-15(22(17)21-16)13-8-10-18-11-9-13/h6-12,14H,1-5H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	118	n/a	n/a	n/a	n/a	7.5	22
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9284319 (2016) BindingDB Entry DOI: 10.7270/Q2765D6D
					More data for this Ligand-Target Pair
Glutathione S-transferase A1/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] (Homo sapiens (Human))	BDBM214645 (US9284319, R2 | US9730929, Example R3 | US9783543,...) Show SMILES C1CCC(CC1)Nc1ccc2ncc(-c3ccncc3)n2n1 Show InChI InChI=1S/C17H19N5/c1-2-4-14(5-3-1)20-16-6-7-17-19-12-15(22(17)21-16)13-8-10-18-11-9-13/h6-12,14H,1-5H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	7.5	22
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9284319 (2016) BindingDB Entry DOI: 10.7270/Q2765D6D
					More data for this Ligand-Target Pair