Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D]' and Ligand = 'BDBM259288'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] (Homo sapiens (Human))	BDBM259288 (US9499547, 29) Show SMILES CC(C)(N)COc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H18N4O2/c1-18(2,19)11-23-17-8-7-16-20-10-13(22(16)21-17)15-9-12-5-3-4-6-14(12)24-15/h3-10H,11,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.5	22
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...				US Patent US9499547 (2016) BindingDB Entry DOI: 10.7270/Q2736PVK
					More data for this Ligand-Target Pair
Glutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] (Homo sapiens (Human))	BDBM259288 (US9499547, 29) Show SMILES CC(C)(N)COc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C18H18N4O2/c1-18(2,19)11-23-17-8-7-16-20-10-13(22(16)21-17)15-9-12-5-3-4-6-14(12)24-15/h3-10H,11,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	7.5	22
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...				US Patent US9499547 (2016) BindingDB Entry DOI: 10.7270/Q2736PVK
					More data for this Ligand-Target Pair