Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833]' and Ligand = 'BDBM256670'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833] (Homo sapiens (Human))	BDBM256670 (US9487511, 49) Show SMILES Cc1nnc(NC(=O)c2csc(c2)[C@H]2C[C@H]2NC2CCOCC2)s1 |r| Show InChI InChI=1S/C16H20N4O2S2/c1-9-19-20-16(24-9)18-15(21)10-6-14(23-8-10)12-7-13(12)17-11-2-4-22-5-3-11/h6,8,11-13,17H,2-5,7H2,1H3,(H,18,20,21)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	8.0	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...				US Patent US9487511 (2016) BindingDB Entry DOI: 10.7270/Q2V123Q4
					More data for this Ligand-Target Pair