Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycine receptor subunit beta' and Ligand = 'BDBM50464248'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine receptor subunit beta (Homo sapiens (Human))	BDBM50464248 (CHEMBL4290217) Show SMILES Fc1ccccc1CN1CCN(CC1)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H19FN2O4S/c19-16-4-2-1-3-14(16)12-20-7-9-21(10-8-20)26(22,23)15-5-6-17-18(11-15)25-13-24-17/h1-6,11H,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...				Eur J Med Chem 137: 63-75 (2017) Article DOI: 10.1016/j.ejmech.2017.05.036 BindingDB Entry DOI: 10.7270/Q2H134PC
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