Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50162083 ((5-Methyl-1H-pyrazol-3-yl)-(2-phenyl-quinazolin-4-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of Glycogen synthase kinase-3 | J Med Chem 48: 1278-81 (2005) Article DOI: 10.1021/jm0492249 BindingDB Entry DOI: 10.7270/Q2X92F1P | |||||||||||
More data for this Ligand-Target Pair |