Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glycogen synthase kinase-3 (Homo sapiens (Human)) | BDBM50229962 (1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea | ...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
Stellenbosch University Curated by ChEMBL | Assay Description Inhibition of recombinant human GSK3alpha/beta using biotin-AAEELDSRAGS(PO3H2)PQL as substrate preincubated for 10 to 15 mins followed by [gamma-33P]... | Bioorg Med Chem Lett 29: 1597-1600 (2019) Article DOI: 10.1016/j.bmcl.2019.04.049 BindingDB Entry DOI: 10.7270/Q25X2DBP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |