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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM342112'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 alpha


(Homo sapiens (Human))		BDBM342112
PNG
(3-((4-((4-(3-(1,3-Di-tert-butyl-1H-pyrazol-5-yl)ur...)
Show SMILES COCCOCCOCCNC(=O)c1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4C(C)(C)C)C(C)(C)C)c4ccccc34)n2)cc(c1)C#C
Show InChI InChI=1S/C42H50N8O6/c1-9-28-24-29(38(51)43-18-19-54-22-23-55-21-20-53-8)26-30(25-28)45-39-44-17-16-37(48-39)56-34-15-14-33(31-12-10-11-13-32(31)34)46-40(52)47-36-27-35(41(2,3)4)49-50(36)42(5,6)7/h1,10-17,24-27H,18-23H2,2-8H3,(H,43,51)(H,44,45,48)(H2,46,47,52)
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US Patent
n/an/a 1.31E+4n/an/an/an/an/an/a



TOPIVERT PHARMA LIMITED; RESPIVERT LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against the GSK 3-alpha enzyme isoform (Invitrogen), are evaluated by determining the level o...

US Patent US9771353 (2017)


BindingDB Entry DOI: 10.7270/Q2HQ4219
More data for this
Ligand-Target Pair