Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 alpha (Homo sapiens (Human)) | BDBM50150699 (3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by ... | Eur J Med Chem 171: 221-234 (2019) Article DOI: 10.1016/j.ejmech.2019.03.039 BindingDB Entry DOI: 10.7270/Q2VH5S4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 alpha (Homo sapiens (Human)) | BDBM50150699 (3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of GSK3alpha (unknown origin) | Drug Metab Dispos 41: 714-26 (2013) Article DOI: 10.1124/dmd.112.048488 BindingDB Entry DOI: 10.7270/Q2FT8NS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 alpha (Homo sapiens (Human)) | BDBM50150699 (3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Curated by ChEMBL | Assay Description Inhibition of human GSK-3alpha using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured in presence of [gamma-33P]ATP by radiometric assay | Eur J Med Chem 171: 221-234 (2019) Article DOI: 10.1016/j.ejmech.2019.03.039 BindingDB Entry DOI: 10.7270/Q2VH5S4R | |||||||||||
More data for this Ligand-Target Pair |