Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM8235'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM8235 (3-[(3-hydroxyphenyl)amino]-4-(2-nitrophenyl)-2,5-d...) Show SMILES Oc1cccc(NC2=C(C(=O)NC2=O)c2ccccc2N(=O)=O)c1 |t:7| Show InChI InChI=1S/C16H11N3O5/c20-10-5-3-4-9(8-10)17-14-13(15(21)18-16(14)22)11-6-1-2-7-12(11)19(23)24/h1-8,20H,(H2,17,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals					Assay Description The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...				Bioorg Med Chem Lett 11: 635-9 (2001) Article DOI: 10.1016/s0960-894x(00)00721-6 BindingDB Entry DOI: 10.7270/Q2QV3JRC
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