Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM8290'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM8290 (3-(2,3-dihydro-1H-indol-1-yl)-4-(3-nitrophenyl)-2,...) Show SMILES O=C1NC(=O)C(=C1N1CCc2ccccc12)c1cccc(c1)N(=O)=O |c:5| Show InChI InChI=1S/C18H13N3O4/c22-17-15(12-5-3-6-13(10-12)21(24)25)16(18(23)19-17)20-9-8-11-4-1-2-7-14(11)20/h1-7,10H,8-9H2,(H,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	7.0	22
SmithKline Beecham Pharmaceuticals					Assay Description The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...				Chem Biol 7: 793-803 (2000) Article DOI: 10.1016/s1074-5521(00)00025-9 BindingDB Entry DOI: 10.7270/Q2M32T0X
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