Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM8346'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha (Homo sapiens (Human))	BDBM8346 (6-aryl-pyrazolo[3,4-b]pyridine analogue 10 | N-[6-...) Show SMILES Oc1ccccc1-c1ccc2c(NC(=O)C3CC3)n[nH]c2n1 Show InChI InChI=1S/C16H14N4O2/c21-13-4-2-1-3-10(13)12-8-7-11-14(17-12)19-20-15(11)18-16(22)9-5-6-9/h1-4,7-9,21H,5-6H2,(H2,17,18,19,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	7.0	22
GlaxoSmithKline					Assay Description The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...				Bioorg Med Chem Lett 13: 3055-7 (2003) Article DOI: 10.1016/s0960-894x(03)00645-0 BindingDB Entry DOI: 10.7270/Q26T0JVK
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