Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM442924'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442924 (US10653688, Compound 103) Show SMILES FC1(CNc2cncc(n2)-c2ccc3cnc(NC(=O)C4CC4)cc3c2)CNC1 Show InChI InChI=1S/C21H21FN6O/c22-21(10-24-11-21)12-26-19-9-23-8-17(27-19)14-3-4-15-7-25-18(6-16(15)5-14)28-20(29)13-1-2-13/h3-9,13,24H,1-2,10-12H2,(H,26,27)(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair