Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50291344'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50291344 (CHEMBL4165510) Show SMILES Fc1cc2CN(C=O)C(Cn3cc(C4=C(C(=O)NC4=O)c4cnc5ccccn45)c(c1)c23)N1CCCCC1 |t:13| Show InChI InChI=1S/C28H25FN6O3/c29-18-10-17-13-34(16-36)23(32-7-3-1-4-8-32)15-33-14-20(19(11-18)26(17)33)24-25(28(38)31-27(24)37)21-12-30-22-6-2-5-9-35(21)22/h2,5-6,9-12,14,16,23H,1,3-4,7-8,13,15H2,(H,31,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibition of recombinant GSK3-beta (unknown origin) assessed as decrease in phosphorylation of CREB at serine-129 in presence of ATP[gamma-33P] by f...				Eur J Med Chem 144: 843-858 (2018) Article DOI: 10.1016/j.ejmech.2017.11.103 BindingDB Entry DOI: 10.7270/Q2Q242SG
					More data for this Ligand-Target Pair