Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM7449'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Porcine)	BDBM7449 (pyrrolocarbazole deriv. 27a | {[({2,4-dimethyl-1,3...) Show SMILES CN1C(=O)c2c(C1=O)c(CNC(=O)C[NH+](C)C)c1c3ccccc3[nH]c1c2C Show InChI InChI=1S/C21H22N4O3/c1-11-16-18(21(28)25(4)20(16)27)13(9-22-15(26)10-24(2)3)17-12-7-5-6-8-14(12)23-19(11)17/h5-8,23H,9-10H2,1-4H3,(H,22,26)/p+1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	30
CNRS					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem 13: 2263-83 (2005) Article DOI: 10.1016/j.bmc.2004.12.045 BindingDB Entry DOI: 10.7270/Q2VQ30VZ
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