Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Co. Curated by ChEMBL | Assay Description Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT). | J Med Chem 38: 1837-40 (1995) Article DOI: 10.1021/jm00011a001 BindingDB Entry DOI: 10.7270/Q23J3GPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Company Curated by ChEMBL | Assay Description Inhibition activity against N-myristoyltransferase (NMT) of candida albicans. | J Med Chem 40: 2609-25 (1997) Article DOI: 10.1021/jm970094w BindingDB Entry DOI: 10.7270/Q2BR8VXS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Co. Curated by ChEMBL | Assay Description Inhibitory activity against Candida albicans N-Myristoyltransferase (NMT). | J Med Chem 38: 1837-40 (1995) Article DOI: 10.1021/jm00011a001 BindingDB Entry DOI: 10.7270/Q23J3GPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Inhibition of Candida albicans N-myristoyltransferase (NMT) with peptide GNAASARR-NH2 and [3H]myristoyl-CoA at 1 uM | Citation and Details BindingDB Entry DOI: 10.7270/Q2FJ2JXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center Curated by ChEMBL | Assay Description Inhibitory activity against Candida albicans N-myristoyltransferase (CaNmt) | Bioorg Med Chem Lett 11: 1833-7 (2001) BindingDB Entry DOI: 10.7270/Q2KS6TRW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Company Curated by ChEMBL | Assay Description Inhibition activity against N-myristoyltransferase (NMT) of human. | J Med Chem 40: 2609-25 (1997) Article DOI: 10.1021/jm970094w BindingDB Entry DOI: 10.7270/Q2BR8VXS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
G.D. Searle and Co. Curated by ChEMBL | Assay Description Inhibitory activity against human N-Myristoyltransferase (NMT). | J Med Chem 38: 1837-40 (1995) Article DOI: 10.1021/jm00011a001 BindingDB Entry DOI: 10.7270/Q23J3GPZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Tested for Inhibitory concentration against human N-myristoyltransferase (NMT) in radiochemical HPLC end point assay with peptide GNAASARR-NH2 and [3... | Citation and Details BindingDB Entry DOI: 10.7270/Q2FJ2JXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human)) | BDBM50034993 ((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | >1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center Curated by ChEMBL | Assay Description Inhibitory activity against human N-myristoyltransferase (HsNmt) | Bioorg Med Chem Lett 11: 1833-7 (2001) BindingDB Entry DOI: 10.7270/Q2KS6TRW | |||||||||||
More data for this Ligand-Target Pair |