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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50081140'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)		BDBM50081140
PNG
(7-Chloro-3-(3,5-dimethyl-phenyl)-4-(4-methyl-morph...)
Show SMILES CN1CCOC(COc2c(-c3cc(C)cc(C)c3)c(=O)[nH]c3cc(Cl)ccc23)C1
Show InChI InChI=1S/C23H25ClN2O3/c1-14-8-15(2)10-16(9-14)21-22(29-13-18-12-26(3)6-7-28-18)19-5-4-17(24)11-20(19)25-23(21)27/h4-5,8-11,18H,6-7,12-13H2,1-3H3,(H,25,27)
KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [125I]-Buserelin to GnRH receptor in rat pituitary membranes.

Bioorg Med Chem Lett 9: 2615-20 (1999)


BindingDB Entry DOI: 10.7270/Q2TD9WK0
More data for this
Ligand-Target Pair