BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50109205'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50109205 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity against human GnRH receptor expressed in HEK293 cells using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt GnRH as radioligand.				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50109205 (8-Cyano-1-(2-fluoro-benzyl)-7-(4-methoxy-phenyl)-6...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound against gonadotropin-releasing hormone receptor of rat				Bioorg Med Chem Lett 12: 399-402 (2002) BindingDB Entry DOI: 10.7270/Q28W3CMT
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair