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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50109239'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50109239
PNG
(3-(4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-1-(2-fluo...)
Show SMILES CN(CCc1ccccn1)Cc1c(cc2n(Cc3ccccc3F)cc(C3=NC(C)(C)CO3)c(=O)n12)-c1ccc(cc1)[N+]([O-])=O |t:28|
Show InChI InChI=1S/C34H33FN6O4/c1-34(2)22-45-32(37-34)28-20-39(19-24-8-4-5-10-29(24)35)31-18-27(23-11-13-26(14-12-23)41(43)44)30(40(31)33(28)42)21-38(3)17-15-25-9-6-7-16-36-25/h4-14,16,18,20H,15,17,19,21-22H2,1-3H3
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PC cid
PC sid
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Similars
PubMed
 270n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human gonadotropin-releasing hormone (hGnRH) receptor expressed in HEK293 cells using des-Gly10[125I-Tyr,5DLeu,6NMeLeu,7Pro9-NEt]...

Bioorg Med Chem Lett 12: 403-6 (2002)


BindingDB Entry DOI: 10.7270/Q2542MXV
More data for this
Ligand-Target Pair