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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50109259'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50109259
PNG
(7-(4-Butyrylamino-phenyl)-1-(2-fluoro-benzyl)-6-{[...)
Show SMILES CCCC(=O)Nc1ccc(cc1)-c1cc2n(Cc3ccccc3F)cc(C(=O)NC3CCCCC3)c(=O)n2c1CN(C)CCc1ccccn1
Show InChI InChI=1S/C40H45FN6O3/c1-3-11-37(48)43-32-19-17-28(18-20-32)33-24-38-46(25-29-12-7-8-16-35(29)41)26-34(39(49)44-31-14-5-4-6-15-31)40(50)47(38)36(33)27-45(2)23-21-30-13-9-10-22-42-30/h7-10,12-13,16-20,22,24,26,31H,3-6,11,14-15,21,23,25,27H2,1-2H3,(H,43,48)(H,44,49)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
 32n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human gonadotropin-releasing hormone (hGnRH) receptor expressed in HEK293 cells using des-Gly10[125I-Tyr,5DLeu,6NMeLeu,7Pro9-NEt]...

Bioorg Med Chem Lett 12: 403-6 (2002)


BindingDB Entry DOI: 10.7270/Q2542MXV
More data for this
Ligand-Target Pair