BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50155354'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50155354 (7-Chloro-4-[2-(1-methyl-5-oxo-pyrrolidin-2-yl)-eth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin releasing hormone receptor expressed in CHO cells was determined by using [125I]-buserelin as radioligand				Bioorg Med Chem Lett 14: 5599-603 (2004) Article DOI: 10.1016/j.bmcl.2004.08.056 BindingDB Entry DOI: 10.7270/Q20V8C8D
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50155354 (7-Chloro-4-[2-(1-methyl-5-oxo-pyrrolidin-2-yl)-eth...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells expressing GnRH receptor				Bioorg Med Chem Lett 14: 5599-603 (2004) Article DOI: 10.1016/j.bmcl.2004.08.056 BindingDB Entry DOI: 10.7270/Q20V8C8D
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair