BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50213664'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50213664 ((S)-5-(2-(2-(2-(3,5-dimethylphenyl)-5-(2-(2-fluoro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-Tyr5, DLeu6, NMeLeu7, Pro-N-Et-GnRH from cloned rat GnRHR				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50213664 ((S)-5-(2-(2-(2-(3,5-dimethylphenyl)-5-(2-(2-fluoro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human GnRHR expressed in RBL cells assessed as inhibition of GnRH-stimulated [3H]-inositol phosphate hydrolysis				Bioorg Med Chem Lett 17: 3845-50 (2007) Article DOI: 10.1016/j.bmcl.2007.05.009 BindingDB Entry DOI: 10.7270/Q2JD4WHQ
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair