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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50215215'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215215
PNG
(1-(2,6-difluorobenzyl)-6-(4-chlorobenzyl)-3-(((R)-...)
Show SMILES Fc1cccc(F)c1Cn1c2CCN(Cc3ccc(Cl)cc3)Cc2c(=O)n(C[C@@H]2CCCN(C[C@@H]3CCCN3Cc3ccccn3)C2)c1=O
Show InChI InChI=1S/C38H43ClF2N6O2/c39-29-13-11-27(12-14-29)20-44-19-15-36-33(25-44)37(48)47(38(49)46(36)26-32-34(40)9-3-10-35(32)41)22-28-6-4-17-43(21-28)24-31-8-5-18-45(31)23-30-7-1-2-16-42-30/h1-3,7,9-14,16,28,31H,4-6,8,15,17-26H2/t28-,31+/m1/s1
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Similars
Article
PubMed
 1.37E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair