BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM50222869'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50222869 (6-(4-fluorophenoxy)-3-{[(3S)-1-isopropylpiperidin-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Prosidion Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation counting				Bioorg Med Chem Lett 22: 2271-8 (2012) Article DOI: 10.1016/j.bmcl.2012.01.078 BindingDB Entry DOI: 10.7270/Q20G3KMP
Prosidion Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Ovis aries)	BDBM50222869 (6-(4-fluorophenoxy)-3-{[(3S)-1-isopropylpiperidin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assay				J Med Chem 50: 5202-16 (2007) Article DOI: 10.1021/jm070071+ BindingDB Entry DOI: 10.7270/Q2WH2QT2
Bayer Pharmaceuticals Corporation Curated by ChEMBL					More data for this Ligand-Target Pair